Cyrine Abdelnour was born in Beirut. She was educated in Saints-Coeur school in Lebanon, where she took a course in Fashion Design. In 1993 she started her modeling career and modeled for many fashion designers. Abdelnour has also starred in Arabic TV serials and films since the late 1990s.
Her first album, Leila Min Layali, was released in 2004. She released her second album, Aleik Ayouni in 2006, with debut single Law Bas Fe Aini becoming one of the most popular Lebanese songs. In 2012 Cyrine starred in the Lebanese Series "Ruby".